In the final days before the Station 19 captaincy is announced, Pruitt warns Andy not to be disappointed with the outcome. Meanwhile, Ben gets upset with Pruitt for having told Bailey the dangers of firefighting; and the team gets trapped inside the garage of a burning house, putting several lives at risk.

Bill joins the military group formed by Ethan, Dominic and Michael. The three men hold a young alien hostage, Isla. Catherine, Sophia and Nathan continue to search for Bill. Adina, and the aliens also set out to find Bill. Chloe accuses the blow when she realizes that Sacha killed Ash. She suggests to her increasingly unstable son to run away with her.

At the university, Sophia watches the videos recorded by Dylan, a young man they found dead, while Catherine focuses on the algorithms he left behind and which decipher the behavior of robots. Thanks to Bill's intervention, Isla manages to flee and join her family.

Inside the Wall, Tim – imprisoned and tortured on the Duke's orders – is convinced by his cellmate Jean-Pierre to write letters calling for revolution. They are rescued by Cherie and her fellow rebels, and prepare to overthrow the Duke. Tim and Cherie spend a passionate night together, and copies of Tim's letters spread throughout the Wall, drawing people to their cause; Cherie urges Tim to lead them. As the Duke addresses a congregation, his sheriff spots Tim in the crowd and attacks, killing Jean-Pierre. Tim unites the oppressed inhabitants of the Wall in an open rebellion. The Duke floods the lower levels, drowning countless people; a farmer named Steven is unable to save his beloved mouse, Molly.

Inside the Wall, Tim – imprisoned and tortured on the Duke's orders – is convinced by his cellmate Jean-Pierre to write letters calling for revolution. They are rescued by Cherie and her fellow rebels, and prepare to overthrow the Duke. Tim and Cherie spend a passionate night together, and copies of Tim's letters spread throughout the Wall, drawing people to their cause; Cherie urges Tim to lead them. As the Duke addresses a congregation, his sheriff spots Tim in the crowd and attacks, killing Jean-Pierre. Tim unites the oppressed inhabitants of the Wall in an open rebellion. The Duke floods the lower levels, drowning countless people; a farmer named Steven is unable to save his beloved mouse, Molly.

When the Pupa turns orange, Korvo realizes he left important Pupa information in his wallet on Shlorp. He and Terry travel back in time to the day they evacuated Shlorp, and knock Korvo's wallet into their spaceship. Returning to the present, they realize the Pupa merely ate something orange, but the time stream has been altered and they now live with Vanbo, an obnoxious Shlorpian. Returning to the past to set things right, Korvo and Terry learn they did not want each other as evacuation partners, but reconcile and beat up Vanbo. Yumyulack discovers Jesse has simulated a nicer version of himself in the "Pretend-O-Deck". His simulated self teaches him to be a better brother to Jesse, but one Yumyulack kills the other.

At the university, Sophia watches the videos recorded by Dylan, a young man they found dead, while Catherine focuses on the algorithms he left behind and which decipher the behavior of robots. Thanks to Bill's intervention, Isla manages to flee and join her family.

Richard and the attendings set out to make Eliza's first day at Grey Sloan a bumpy one. Meanwhile, Meredith tries to track down Alex.

Maggie gets a surprise visit from her mother at the hospital. Bailey has to make a difficult decision when one of the attendings refuses to work with Eliza, and Stephanie gets caught up in Owen and Amelia's personal drama.

Lynette kicks Tom out of her chemotherapy sessions. Susan is mistaken for a stripper. Bree attempts to steal a prize-winning recipe from Katherine.

Bree informs the housewives of what she overheard in the Mayfair house. Stella makes some special brownies to help Lynette through chemotherapy. Susan throws a charades party for the whole neighborhood.

The doctors of Chastain are surrounded by new rules and doctors, as Red Rock Mountain Medical takes over the hospital. Conrad finds himself in a dangerous situation when the construction for a new neurosurgery center causes a gas explosion at Chastain. Meanwhile, new hotshot neurosurgeon Barrett Cain, is put to the test with a complicated surgery and Mina acts as a support for Nic, who is struggling with a devastating loss.

Richard and the attendings set out to make Eliza's first day at Grey Sloan a bumpy one. Meanwhile, Meredith tries to track down Alex.

Maggie gets a surprise visit from her mother at the hospital. Bailey has to make a difficult decision when one of the attendings refuses to work with Eliza, and Stephanie gets caught up in Owen and Amelia's personal drama.

Lynette kicks Tom out of her chemotherapy sessions. Susan is mistaken for a stripper. Bree attempts to steal a prize-winning recipe from Katherine.

Bree informs the housewives of what she overheard in the Mayfair house. Stella makes some special brownies to help Lynette through chemotherapy. Susan throws a charades party for the whole neighborhood.

When Cain tries to be a hero at a crash scene, he is struck by a car, causing Chastain’s doctors to put aside their personal issues to try and save his life. Conrad and Nic team up to help one of the crash victims, whose secretive past makes it difficult to identify a diagnosis. Meanwhile, Bell brings his TV crew to the hospital in hopes of garnering positive attention for Chastain, and Mina opens up to Nic, only to find out that Nic is holding on to a secret of her own.

Cain tries to recruit Bell and Kit to join him on a dangerous surgery, with the intent of garnering publicity for the hospital. Meanwhile, the Raptor finds himself with an emotional attachment to a patient whose life is put in his hands and Mina's friend, Adaku (guest star Erinn Westbrook), arrives at the hospital with shocking news. Also, Devon rotates out of the ER and Nic plans a surprise for Conrad

The residents are excited for Eliza's next phase of teaching, but they spend the day caught between the warring attendings. Meanwhile, April has a challenging first day in her new role at the hospital.

Alex returns to the hospital and discovers a lot has changed since he left. Meanwhile, Jo has to make a difficult decision on a case, and Arizona tries to distance herself from Eliza

Edie is shocked when she receives some news at the gynecologist's office. At the baby shower Bree's friends throw her, Bree's ex-mother-in-law Phyllis discovers her pregnancy is a hoax. Finally, Wisteria Lane welcomes to the street a homosexual couple.

Bob & Lee's contemporary water sculpture in their front yard prompts the Wisteria Lane neighborhood association into action. Edie finds out about the affair that Carlos is having with Gaby. Also, John Rowland wants to rekindle his romance with Gaby.

In the final days before the Station 19 captaincy is announced, Pruitt warns Andy not to be disappointed with the outcome. Meanwhile, Ben gets upset with Pruitt for having told Bailey the dangers of firefighting; and the team gets trapped inside the garage of a burning house, putting several lives at risk.

While Kate comes under fire from D.A. Russell, Megan has cracked the case but can't tell her team. As long as the killer has Lacey, Megan must keep what she's learned to herself.

As Megan returns to work months after Peter's death, she is thrown together on a new case with a detective from her past. A serial killer is seeking out young war veterans but the case hits close to home for Megan when the killer takes Lacey hostage.

When Cain tries to be a hero at a crash scene, he is struck by a car, causing Chastain’s doctors to put aside their personal issues to try and save his life. Conrad and Nic team up to help one of the crash victims, whose secretive past makes it difficult to identify a diagnosis. Meanwhile, Bell brings his TV crew to the hospital in hopes of garnering positive attention for Chastain, and Mina opens up to Nic, only to find out that Nic is holding on to a secret of her own.

Rosie, Villa and TMI head to a small town to investigate the murder of its former mayor. Rosie struggles with feelings of guilt, as Slade faces complications following his kidney donation.

While Kate comes under fire from D.A. Russell, Megan has cracked the case but can't tell her team. As long as the killer has Lacey, Megan must keep what she's learned to herself.

When Cain tries to be a hero at a crash scene, he is struck by a car, causing Chastain’s doctors to put aside their personal issues to try and save his life. Conrad and Nic team up to help one of the crash victims, whose secretive past makes it difficult to identify a diagnosis. Meanwhile, Bell brings his TV crew to the hospital in hopes of garnering positive attention for Chastain, and Mina opens up to Nic, only to find out that Nic is holding on to a secret of her own.

In the final days before the Station 19 captaincy is announced, Pruitt warns Andy not to be disappointed with the outcome. Meanwhile, Ben gets upset with Pruitt for having told Bailey the dangers of firefighting; and the team gets trapped inside the garage of a burning house, putting several lives at risk.

Edie is shocked when she receives some news at the gynecologist's office. At the baby shower Bree's friends throw her, Bree's ex-mother-in-law Phyllis discovers her pregnancy is a hoax. Finally, Wisteria Lane welcomes to the street a homosexual couple.

Lynette's sisters Lydia and Lucy come to visit. While having dinner with Susan and Mike, Bree and Orson realize they share different views on whether their newborn baby should be circumcised. On a boat, Victor confronts Gaby about her affair with Carlos and she throws him into the ocean. Later, Bree informs Susan that she thinks Mike is addicted to drugs.

Richard, Jackson, April and Catherine tackle a grueling trauma case intensified by hospital politics. Amelia finally faces her feelings about Owen, and Meredith gets caught between Nathan and Alex over a patient.

Jackson and April travel to Montana in order to perform a complicated surgery on a young patient, but Jackson's mind is elsewhere, and April is forced to step up and get him back on track.

When a police officer shows up to the ER with an injured criminal that he caught in the act, it's up to the Chastain staff to keep him alive in order to save an innocent life. Nic gets roped into a surgical rotation with Cain that leaves her questioning the way he operates, and Conrad makes a shocking discovery about the hospital. Meanwhile, Bell pursues a new fiscal venture that may bring him into a whole new market.