Chastain picks up the pieces after the fall out with the corrupt medical device company Quovadis, leaving Marshall ready to charter new territory in the medical field, and Devon to finally discover the truth about what happened to Julian Booth. As Conrad and Alec team up to help a young gymnast experiencing mysterious symptoms, Nic focuses on her sister, who's back with their estranged father, Kyle, in tow. Meanwhile, Bell rushes to Kit's aid when her ex-husband comes to the ER needing emergency surgery.

When Atlanta is struck by a severe snowstorm, Mina must perform a big surgery – without the help of The Raptor – to save the life of a young father, while Kit and Bell get stuck babysitting the man's children. Nic and Conrad experience a disagreement with a patient's treatment, causing further strain in their relationship. Meanwhile, Devon teaches an important lesson about life and death to a first-year med student.

Devon grows concerned when a mother's complaints go unaddressed after her delivery, and pushes Bell to take drastic measures. Conrad is faced with breaking the news to Nic regarding Jessie's worsening condition. Meanwhile, The Raptor, Mina and Kit spring into action when a mother and son enter the ER with devastating injuries.

Devon grows concerned when a mother's complaints go unaddressed after her delivery, and pushes Bell to take drastic measures. Conrad is faced with breaking the news to Nic regarding Jessie's worsening condition. Meanwhile, The Raptor, Mina and Kit spring into action when a mother and son enter the ER with devastating injuries.

When the hospital has a severe blood shortage, Conrad must try every avenue to save a patient's life. Nic receives devastating news and is left worrying about her sister's health, while Mina and Devon work with a new anesthesiologist who is not what she seems. Elsewhere, Kit considers the future of her intertwining relationships and Bell has an encounter with a woman from his past.

After a catastrophic bridge collapse sends dozens of victims to Grey Sloan, the hospital activates its full disaster response as they race to treat a surge of critically injured patients.

When one of Grey Sloan's own lands in the hospital, Bailey tries to figure out what happened while the rest of the doctors jump in to help. Meredith juggles huge secrets that affect her relationships with Alex and Maggie. While Richard helps Jo with a big decision, April and Catherine clash over the new baby.

Meredith considers her loyalties, as Alex deals with the repercussions of his actions. Newlyweds Amelia and Owen host a dinner party with unlikely guests, and Jackson proposes an arrangement to help April through her recovery.

A car crash at a funeral brings a bickering family into the hospital. Back from New York, Arizona ends up caught between Alex and Andrew. While Ben takes on a new parenting role, Amelia helps Meredith and Maggie through a problem.

Upon the arrival of Batallion Chief Frankel, Jack begins his first shift as co-captain and continues to butt heads with Andy on leadership styles. Captain Pruitt has a difficult time following doctor’s orders and winds up back at the station to take on administrative duties. Meanwhile, the rest of the team at Station 19 responds to an attic fire at JJ’s apartment building and a call to a pool house party.

As if being co-captains weren’t hard enough, Andy and Jack find themselves in disagreement over spending decisions at the station. Meanwhile, the firefighters respond to a structure fire at a brand-new bed-and-breakfast; and Ryan calls Maya when he finds her brother in some trouble.

Miranda Bailey visits Ben at work, meeting his new co-workers for the first time. While most of the team responds to a motor vehicle accident involving an electrical danger, Andy and Maya are paired up to go on their first stakeout.

Ian proposes to Susan. The Scavo pizzeria prepares for its grand opening. Mike visits a hypnotherapist in hopes of remembering Monique. Gabrielle's romantically interested in a lawyer, but he's working for Zach who wants her for himself. Bree is hospitalized after a fall, after being tricked to climb on a ladder to retrieve Monique's teeth.

All of Wisteria Lane gathers at Pizzeria Scavo for the grand opening event, while one resident meets an untimely fate and another accepts a marriage proposal.

When a city-wide outbreak of a mysterious and lethal virus occurs, even Megan and her team are at risk. In order to determine who and what caused this outbreak, CDC Officer Charlie Stafford takes over the investigation.

When the team responds to an apartment fire, Captain Pruitt takes a hit, the future of the station’s leadership is in jeopardy and firefighter Andy Herrera is forced to step up. Meanwhile, new recruit Ben Warren is trading in the scalpel for a fresh start as a firefighter, but it hasn’t been easy and he has a hard time realizing that emergencies in the field are vastly different than those at Grey Sloan Memorial.

With the absence of Captain Pruitt, Andy and Jack try to navigate how to work together, and a car accident on a rural road puts both the victims and the crew’s lives at risk.

When a son discovers his murdered parents, the team soon realizes that this perfect family wasn't really perfect. Megan has a new love interest and Curtis is grappling with his new position.

A case of mistaken identity mars a case when two young girls are in a tragic car accident. The wrong girl may have been pronounced dead and the actual cause of death is in question.

When a city-wide outbreak of a mysterious and lethal virus occurs, even Megan and her team are at risk. In order to determine who and what caused this outbreak, CDC Officer Charlie Stafford takes over the investigation.

As the Major Crimes team desperately seek answers amidst a string of unresolved crimes, Morgan suspects the Game Maker is responsible. Meanwhile, Daphne and Oz set out to find Roman, and Elliot prepares a surprise act for his school’s talent show.

Rosewood and Villa head back to Villa’s roots in Little Havana to investigate a vigilante who may be guilty of murder. Villa learns that her brother, Marcos, has a surprising connection to the case, and Rosie receives news of a complication regarding his kidney transplant.

When Cain’s elective surgery patient returns with complications, Mina and Raptor butt heads over how to handle the situation. Conrad and Devon treat a local Congresswoman who withholds information that could prevent her from receiving proper treatment, causing Devon to open up about his grief. In the wake of losing many colleagues to the virus, Bell worries who would be there for him in a moment of crisis and finds himself mining his own past to find his estranged former stepson, elite plastic surgeon Dr. Jake Wong (guest star Conrad Ricamora). Meanwhile, Logan Kim finds himself on the chopping block when the doctors are questioned about his actions during the pandemic.

Alex tries to do the right thing but still can't catch a break. Jackson and April adjust to their "new normal" with the baby. While Meredith and Nathan establish what's going on between them, Amelia questions the state of her relationship with Owen.

Susan goes into the woods to try to find Mike. Gabrielle gets into an argument with a meter man who gives her a ticket. Victor is elected mayor, and Gabrielle goes back to teach the meter man a lesson. Edie's ex-husband comes back to collect Travers. Lynette realizes she has feelings for another man.

While Tom tries to save his marriage, Mike and Susan get engaged. However, Susan's happiness is short-lived when she realizes Gabrielle has stolen her cancelled wedding with Ian. Meanwhile, Edie wants Carlos to move in with her, and she's ready to do anything to make it happen.

The arrival of a new consultant puts the doctors on edge; Amelia and Owen bring their personal problems into the hospital; April explores some unfamiliar territory.