The crew gathers to face the outcome of a life-threatening situation; Andy and Ben respond to a man impaled by a chandelier; Station 19 is called upon to organize shipments of supplies and assist with wildfires in Los Angeles.

The epic series finale sees the survivors attempt to turn the tables on their aggressors once and for all. Mokrani and Catherine prepare for the fight of their lives. Emily seeks answers, at any cost. And Sacha’s visions continue, giving a confounding glimpse of the future…

London, four months after the attack. The survivors organize the Resistance. Bill continues his research on aliens and understands that their DNA is human but that their organs are degenerating. In France, a severely wounded dissident alien reaches the Observatory

Korvo and Terry place nanobots in the city's water supply to spy on their neighbors. Learning they are not well-liked, Korvo and Terry use the information from the nanobots to win over the community, and run for president of their homeowner association. The nanobots form a sentient person that runs for president as well, and all three expose embarrassing secrets about their neighbors, who break out in violence. The incumbent president Ruth restores order and turns the crowd against Korvo, Terry, and the nanobot person, who escapes from Korvo. Jesse – concerned that Yumyulack is shrinking and capturing too many humans – uses technology to manipulate people who were mean to Yumyulack, hoping to teach him that humans are generally kind.

Korvo, increasingly frustrated by Terry, vomits a "red Goobler" – a stress-induced creature intent on killing Korvo. They buy a Jet Ski from Trent, who is killed by the Goobler. Hunting the creature inside a Halloween store, they shrink and capture it. At school, Jesse discovers a flower growing on her head, which releases pollen similar to MDMA, making the popular girls enamored with her. Yumyulack accompanies Jesse to a party and discovers his own flower, with pollen similar to cocaine, and bonds with the popular boys. The mix of Yumyulack and Jesse's pollen creates an effect similar to PCP or bath salts, turning the party-goers bloodthirsty and deranged. Jesse and Yumyulack inform Terry and Korvo, who explain the flowers are a temporary fungus.

Woohoo! School's out, so the Solars make a splash at summer camp!

The alien’s connection to certain survivors raises difficult questions. Bill makes a startling discovery. Sacha’s behaviour is increasingly erratic. And Tom’s birthday proves cause for celebration. But at what cost?

Conrad finds himself caught between his duties as a doctor and his loyalty to Kit, when he discovers that her son-in-law may be suffering from a serious disease. While moonlighting at a long-term care facility, Devon and Nic make a shocking discovery about a former patient who fell victim to Cain's manipulative practices. Meanwhile, after jumping into a new opportunity as a TV doctor, Bell is left without any surgeries and The Raptor brings him in to help on an important case.

Following a deadly blaze inside a coffee beanery, the members of Station 19 find themselves on high alert as one of their team lands at Grey Sloan, leaving the future uncertain in the face of a life-threatening situation.

Nicollette Sheridan takes her final stroll down Wisteria Lane in unforgettable fashion. As the women look back on Edie’s life, Susan recalls their first meeting, Lynette reflects on a memorable night out, Bree is reminded of the thoughtfulness she bestowed upon Orson, and Gaby remembers fondly a night of friendly competition.

Covering up the truth leads to unexpected consequences. Carlos finds Lynette in a precarious position, which she chooses to hide from Tom; Gaby hastily covers for Tom’s coy behavior; Orson tries to hide the truth about his wounds from Bree; Katherine confesses to Mike, which leads to a surprising realization; and Susan confides her dark secret in Dave.

Conrad finds himself caught between his duties as a doctor and his loyalty to Kit, when he discovers that her son-in-law may be suffering from a serious disease. While moonlighting at a long-term care facility, Devon and Nic make a shocking discovery about a former patient who fell victim to Cain's manipulative practices. Meanwhile, after jumping into a new opportunity as a TV doctor, Bell is left without any surgeries and The Raptor brings him in to help on an important case.

Meredith, still functioning as the interim chief, sees Nick for the first time since she rejected his offer to move to Minnesota; Bailey tells Richard she is not ready to return to work; Levi works up the courage to break disappointing news to Jo.

The attending surgeons and interns work together to solve a medical mystery when a college kid comes in with what first looks like food poisoning but has escalating and dire complications; Jo spends her day off with Bailey.

Nicollette Sheridan takes her final stroll down Wisteria Lane in unforgettable fashion. As the women look back on Edie’s life, Susan recalls their first meeting, Lynette reflects on a memorable night out, Bree is reminded of the thoughtfulness she bestowed upon Orson, and Gaby remembers fondly a night of friendly competition.

Covering up the truth leads to unexpected consequences. Carlos finds Lynette in a precarious position, which she chooses to hide from Tom; Gaby hastily covers for Tom’s coy behavior; Orson tries to hide the truth about his wounds from Bree; Katherine confesses to Mike, which leads to a surprising realization; and Susan confides her dark secret in Dave.

While Melinda is at the University’s botany lab she deals with some telekinetic events while dealing with a plant from Peru that is bleeding. Melinda finds that she must help a Doctor save herself.

When Cain becomes aware of an emergency situation breaking out at the hospital, he recruits Ezra to help keep it under wraps. Also, Nic works to come up with a support system for a patient in need of a lung transplant. Meanwhile, Kitt's son-in-law's condition continues to worsen.

Bailey recruits the interns to create a series of social media videos informing teens about sexual health. The videos, filmed at Grey Sloan in front of a group of high schoolers, hit home as a student has medical complications during her visit. Elsewhere, Meredith and Maggie learn something new about Zola.

It’s Halloween night at Grey Sloan Memorial. Meredith and Nick try to spend some alone time together; Levi is stressed due to overworking, and Winston and Owen have the interns practice trauma training on a real cadaver.

Everyone knows how to bargain. Bree sinks to a new low to retain the best lawyer; Gaby’s vanity is put to the test when she makes a deal with daughter Juanita; Lynette and Tom negotiate sex; Katherine deceives Mike to win his heart; Jackson walks back into Susan’s life with a proposal; and an unexpected visit sends Dave to do some bargaining of his own.

Every day is a masquerade. Bree goes to extremes to hide her true intentions from Orson; Susan and Jackson put on an act for the authorities; Lynette is shocked at the lengths Tom will go to in order to look younger; Katherine masks the truth from Mike, afraid to lose him; and Dave is on edge when he learns a key witness to his misdeeds surfaces.

The crew gathers to face the outcome of a life-threatening situation; Andy and Ben respond to a man impaled by a chandelier; Station 19 is called upon to organize shipments of supplies and assist with wildfires in Los Angeles.

When Rosewood and Villa suspect a brilliant doctor has killed two of his patients, they must find a way to make their case with limited evidence. Meanwhile, Villa spars with Captain Hornstock when he discourages her from pursuing an uncertain case. Also, Rosewood receives an anonymous letter revealing something that could change his life forever.

When Captain Hornstock becomes the prime suspect in his third ex-wife’s murder, he turns to the only two people he can trust to prove his innocence, Rosewood and Villa, forcing them to repair their severely damaged relationship in hopes of clearing his name. Meanwhile, Shirley’s revelations lead to emotional consequences for Rosewood and Pippy.

While Melinda is at the University’s botany lab she deals with some telekinetic events while dealing with a plant from Peru that is bleeding. Melinda finds that she must help a Doctor save herself.

When a priceless painting is stolen in a museum heist, Morgan and Karadec team up with an art-recovery expert to unravel a tangled case and fierce ownership battle. Meanwhile, Soto is determined to uncover the secrets hidden inside Roman’s backpack.

When Captain Hornstock becomes the prime suspect in his third ex-wife’s murder, he turns to the only two people he can trust to prove his innocence, Rosewood and Villa, forcing them to repair their severely damaged relationship in hopes of clearing his name. Meanwhile, Shirley’s revelations lead to emotional consequences for Rosewood and Pippy.

While Melinda is at the University’s botany lab she deals with some telekinetic events while dealing with a plant from Peru that is bleeding. Melinda finds that she must help a Doctor save herself.

The crew gathers to face the outcome of a life-threatening situation; Andy and Ben respond to a man impaled by a chandelier; Station 19 is called upon to organize shipments of supplies and assist with wildfires in Los Angeles.

Everyone knows how to bargain. Bree sinks to a new low to retain the best lawyer; Gaby’s vanity is put to the test when she makes a deal with daughter Juanita; Lynette and Tom negotiate sex; Katherine deceives Mike to win his heart; Jackson walks back into Susan’s life with a proposal; and an unexpected visit sends Dave to do some bargaining of his own.

Every day is a masquerade. Bree goes to extremes to hide her true intentions from Orson; Susan and Jackson put on an act for the authorities; Lynette is shocked at the lengths Tom will go to in order to look younger; Katherine masks the truth from Mike, afraid to lose him; and Dave is on edge when he learns a key witness to his misdeeds surfaces.

Bailey and Addison take a road trip to volunteer at a family planning center, but a patient’s ectopic pregnancy leads to complications. Elsewhere, the interns play detective about Lucas’ relationship with Amelia, and Meredith catches up with Jackson on a trip to Boston.

On the heels of life-changing news, a thunderstorm hits Grey Sloan; the attending surgeons and interns work together to save an injured reporter and family affected by the storm; a beloved author undergoes a risky surgery.

Just when Derek's condition seems to be improving, a severe complication arises, causing Kit to fear that he may be the latest victim of Cain's cover-up. When Cain's former girlfriend is admitted to the hospital for surgery, the doctors finally get a glimpse into his personal life. Meanwhile, Conrad fills in Marshall on the emergency situation facing the hospital and Mina and The Raptor work on saving the heart of a salsa dancer.